![]() ![]() The cause of coagulation disorder is not always clear. In rare cases, the mutation can occur spontaneously or due to another medical problem without a family history of the condition. Most people with von Willebrand’s disease inherit a genetic mutation that affects the production of von Willebrand factor. Due to only having one copy of an X chromosome, males are more likely to develop hemophilia. Males typically possess one X chromosome and one Y chromosome, while females often have two X chromosomes. It is due to a mutation on the X chromosome that affects clotting factors VIII or IX. Genes provide instructions for how the body makes blood clots - some genetic mutations cause the body to make errors when forming blood clots, which can lead to a disorder.įor example, hemophilia is a condition that people usually inherit from a parent. People inherit these genetic changes from their biological parents, or they acquire them after birth. Genetics can cause many types of coagulation disorders. In rare cases, individuals in hypercoagulable states could experience a blood clot that causes a heart attack or stroke. ![]() This disorder causes blood clots to form in a deep vein that can break away and enter the lungs. People in hypercoagulable states are at risk of venous thromboembolism. Some individuals may also experience platelet disorders, which are rare conditions where the body produces too many, too few, or dysfunctional platelets. In rare cases, some people lack other clotting factors that may cause excessive bleeding, such as factors I, II, or V. Babies born with low vitamin K levels who do receive supplements may develop vitamin K deficiencies, which can lead to excessive internal or external bleeding. Vitamin K deficiency bleeding: The body requires vitamin K to form blood clots.Liver disease-associated bleeding: People with liver disease can experience scarring that increases the risk of bleeding disorders or thrombosis.Females are more likely to notice the condition than males due to heavy or bleeding that characterizes the condition during menstrual periods or birth. von Willebrand’s disease: Another genetic disorder that prevents clotting due to insufficient von Willebrand factor, a blood-clotting protein.The most common types are hemophilia A and B, where the body lacks certain proteins in the blood for clotting. It causes excessive bleeding, swelling, and bruising. ![]() Hemophilia: A genetic disorder that passes through families and prevents proper blood clotting.There are many types of coagulation disorders, including the below. ![]()
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